research advances

• Buena VISTA

  A novel immunoglobulin ligand with functions in autoimmunity and cancer surveillance is characterized.

• Anchoring's the way

  New insights into the regulation of AQP0 reveal mechanisms involved in cataract development.

• Metal mates

  Experimental validation of a designed metal-mediated dimer highlights the potential of computational methods.

• Overexpressed problems

  An analysis of the effects of protein overexpression gives insight into the difficulties of preparing intramembrane proteins for crystallization.

• more this month

• featured system

  • Disordered Proteins

    Many proteins use disorder to perform specialized functions, posing special challenges for structural biologists.

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• news

  • PSI in the spotlight
  • The quasicrystal from outer space
  • New year, new science

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• research library

  • The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal
  • Oligomeric State of the Oxalate Transporter, OxlT
  • Accessing protein conformational ensembles using room-temperature X-ray crystallography

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• events

  • Keystone: High-throughput Structural Biology January 22, 2012 - January 27, 2012
    Keystone, CO, USA
  • 56th Biophysical Society Annual Meeting February 25, 2012 - February 29, 2012
    San Diego, California, USA

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