research advances
Synopses of important developments in the field of structural biology and structural genomics, including advances from the Protein Structure Initiative. The featured articles and technical highlights are specially written for the Structural Biology Knowledgebase, while the research highlights are taken from NPG publications.
July 2011
featured articles
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Looking for lipids
The structure of UNC119 by itself and with a substrate shows how it binds lipids to regulate G protein trafficking.
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Seeing HetR
The structure of the transcription factor HetR now indicates how it might function during cyanobacterial differentiatation.
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research highlights
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TH17 cell differentiation inhibitorsNew inhibitors block ROR receptors and inhibit TH17 cell development and activity.
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DNA origami in 3DComplex, curved three-dimensional DNA nanostructures can be created using new DNA origami folding techniques.
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technical highlights
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Rosetta hone
A method using structural modeling tools to improve molecular replacement promises to allow structural determination for cases that resist solution by current methods.
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Structure from sequence
A new computational tool will allow researchers to easily predict RNA structural modules from the sequence alone.
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