research advances

Synopses of important developments in the field of structural biology and structural genomics, including advances from the Protein Structure Initiative. The featured articles and technical highlights are specially written for the Structural Biology Knowledgebase, while the research highlights are taken from NPG publications.

October 2010

  • Selected outreach highlights from PSI-2 (2005-2010)

    • Introduction

      Structural Biology Knowledgebase Outreach Coordinator Margaret Gabanyi introduces the final installment in a series of articles highlighting the achievements of the Protein Structure Initiative 2005–2010.

    • Industrial ties

      The contributions of the Protein Structure Initiative to the development of new technologies, resources and therapeutics through collaborations with industry offer another measure of its success.

    • Know thy enemy … structurally

      Visualizing molecules linked to disease can give insight into how to strike back. All the more reason for aiming to solve structures of these proteins.

    • Function following form

      The genome projects have yielded the sequences of many genes of unknown function. Insight into the mechanisms of action of the products of these genes can come from collaboration between structural biology and follow-up functional analyses..

    • Information sharing

      The Protein Structure Initiative is not just about determining structures—although, ultimately, increased structural coverage will provide far-reaching benefits. The biological community also stands to gain from the great wealth of information and resources that the PSI has to offer.

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